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Table 1 Predisposing factors for developing venous thrombosis and gangrene in cancer patients

From: Venous gangrene and cancer: A cool look at a burning issue

• Supra-therapeutic level of INR ≥ 6.0

• *Acquired Protein C and protein S deficiency as result of warfarin treatment

• *Heparin induced thrombocytopenia, after initiating or continuing warfarin therapy

• *Cancers of the pancreas, lung, stomach and adenocarcinoma of unknown primary.

• *Positive anticardiolipin antibodies

• *Obesity and metabolic syndrome

• Cancer treatment (chemotherapy or hormonal e.g. tamoxifen)

• Surgical operations

  1. *Risk of recurrent thromboembolism