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Table 2

From: Results of a planned interim toxicity analysis with trimodality therapy, including carboplatin AUC = 4, paclitaxel, 5-fluorouracil, amifostine, and radiation for locally advanced esophageal cancer: preliminary analyses and treatment recommendations from the North Central Cancer Treatment Group

Patient Amifostine dose received (%)* Neoadjuvant chemotherapy dose received (%) 1stcycle/2ndcycle* Disease Status
1 31 81/75 CR**
2 7 71/57 CR
3 16 64/11 PR***
4 27 100/26 PR
5 73 100/100 CR
6 24 52/3 CR
7 63 62**** PR
8 87 86**** dead
9 7 91/28 CR
10 67 72/79 CR
  1. *denotes the lowest percentage of administered drug for a cycle
  2. ** complete response (CR)
  3. ***partial response (PR)
  4. ****second cycle not give