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Table 1 AJCC TNM Rectal Cancer Staging

From: The role of endoscopic ultrasound in the evaluation of rectal cancer

TX Primary tumor can not be assessed.
T0 No primary tumor identified.
Tis Carcinoma in situ (tumor limited to mucosa).
T1 Involvement of submucosa, but no penetration through muscularis propria.
T2 Invasion into, but not penetration through, muscularis propria.
T3 Penetration through muscularis propria into subserosa (if present), or pericolic fat, but not into peritoneal cavity or other organs.
T4 Invasion of other organs or involvement of free peritoneal cavity.
NX Nodal metastasis can not be assessed.
N0 No nodal metastasis.
N1 1–3 pericolic/perirectal nodes involved.
N2 4 or more pericolic/perirectal nodes involved.
MX Distant metastasis can not be assessed.
M0 No distant metastases.
M1 Distant metastases