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Table 5 long term results (mean follow up: 44 mo., r. = 18–84)

From: Preoperative bi-fractionated accelerated radiation therapy for combined treatment of locally advanced rectal cancer in a consectutive series of unselected patients

Parameter

No.

%

Deceased (progression of disease)

8

17.0

Primary tumour

2

25

Recurrent disease

6

75

Alive without disease

24

51.0

Alive with disease

15

31.9

Overall local recurrences

10

21.2

Pure distant metastases

13*

27.6

Urogenital toxicity – grade 3

3**

6.3

Gastrointestinal toxicity – grade 3

3***

6.3

  1. * liver 7 cases, lung 4 cases, peritoneum and lymphnodes 2 cases
  2. ** bladder incontinence
  3. *** 1 case of radiation enteritis requiring surgery, 2 cases of anastomotic stricture requiring serial endoscopic dilatations