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Table 1 Predisposing factors for developing venous thrombosis and gangrene in cancer patients

From: Venous gangrene and cancer: A cool look at a burning issue

• Supra-therapeutic level of INR ≥ 6.0
• *Acquired Protein C and protein S deficiency as result of warfarin treatment
• *Heparin induced thrombocytopenia, after initiating or continuing warfarin therapy
• *Cancers of the pancreas, lung, stomach and adenocarcinoma of unknown primary.
• *Positive anticardiolipin antibodies
• *Obesity and metabolic syndrome
• Cancer treatment (chemotherapy or hormonal e.g. tamoxifen)
• Surgical operations
  1. *Risk of recurrent thromboembolism