Figure 2From: Contribution of BRCA1 germline mutation in patients with sporadic breast cancerGermline mutation of exon-13 of BRCA1 with splice site deletion. A: SSCP mobility shift of the amplified region in exon-13. White arrow: wild type from normal controls; dark arrow: mutated product from a patient showing the mobility shift. B: sequence verification of the deleted nucleotide as indicated in A. Arrow indicates the missing nucleotide A in the exon13 splice site.Back to article page