|
Guanine Nucleotide Exchange Factors
|
---|
NPI status
|
TRIO
|
VAV1
|
TIAM-1
|
---|
(NPI < 3.4)
|
109 ± 44
|
0.45 ± 0.22
|
1957 ± 1466
|
(NPI 3.4–5.4)
|
234 ± 113
|
1.18 ± 1.06
|
506 ± 205
|
(NPI > 5.4)
|
315 ± 176
|
0.45 ± 0.41
|
298 ± 123
|
- NPI = Nottingham Prognostic Index.
- Levels of Trio showed a sequential increase with increased NPI status with a significant increase from NPI1 to NPI2 (p = 0.04). Expression of Vav1 showed no definitive pattern while TIAM-1 expression showed a sequential decrease with an increase in NPI status.