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Table 2 Expression levels of the three GEFs studied related to tnm status

From: The expression and prognostic value of the guanine nucleotide exchange factors (GEFs) Trio, Vav1 and TIAM-1 in human breast cancer

 

Guanine Nucleotide Exchange Factors

TNM status

TRIO

VAV1

TIAM-1

1

160 ± 50.5

0.41 ± 0.22

430 ± 117

2

116.5 ± 61.6

1.28 ± 1.04

2613 ± 2245

3

669 ± 544

0.148 ± 0.12

2022 ± 1817

  1. tnm = tumour-node-metastasis.
  2. TIAM-1 expression increased with tumour-node-metastasis (tnm) status as did Vav1 levels however, Trio expression showed an increase from tnm1 to tnm3 (160 ± 50 tnm1 and 669 ± 554 tnm4 p = 0.39) but a decrease in Trio expression in tnm2 tumours (117 ± 62).