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Table 2 Expression levels of the three GEFs studied related to tnm status

From: The expression and prognostic value of the guanine nucleotide exchange factors (GEFs) Trio, Vav1 and TIAM-1 in human breast cancer

  Guanine Nucleotide Exchange Factors
TNM status TRIO VAV1 TIAM-1
1 160 ± 50.5 0.41 ± 0.22 430 ± 117
2 116.5 ± 61.6 1.28 ± 1.04 2613 ± 2245
3 669 ± 544 0.148 ± 0.12 2022 ± 1817
  1. tnm = tumour-node-metastasis.
  2. TIAM-1 expression increased with tumour-node-metastasis (tnm) status as did Vav1 levels however, Trio expression showed an increase from tnm1 to tnm3 (160 ± 50 tnm1 and 669 ± 554 tnm4 p = 0.39) but a decrease in Trio expression in tnm2 tumours (117 ± 62).