|
Guanine Nucleotide Exchange Factors
|
---|
Survival status
|
TRIO
|
VAV1
|
TIAM-1
|
---|
1 Disease free
|
174.1 ± 62.1
|
0.89 ± 0.48
|
60.3
|
2 Metastatic disease
|
263 ± 151
|
0.01 ± 0.003
|
169
|
3 Local recurrance
|
152.4 ± 94.5
|
0.02 ± 0.012
|
26
|
4 Died from breast cancer
|
188.6 ± 97.2
|
0.03 ± 0.016
|
225
|
- Trio levels show little change of expression between patients who survived and patients who died from breast cancer. Vav1expression was highest in patients who remained disease free while TIAM-1 expression was much lower in patients who remained disease free compared with those who died from breast cancer.