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Table 3 Expression levels of the three GEFs studied related to clinical outcome

From: The expression and prognostic value of the guanine nucleotide exchange factors (GEFs) Trio, Vav1 and TIAM-1 in human breast cancer

  Guanine Nucleotide Exchange Factors
Survival status TRIO VAV1 TIAM-1
1 Disease free 174.1 ± 62.1 0.89 ± 0.48 60.3
2 Metastatic disease 263 ± 151 0.01 ± 0.003 169
3 Local recurrance 152.4 ± 94.5 0.02 ± 0.012 26
4 Died from breast cancer 188.6 ± 97.2 0.03 ± 0.016 225
  1. Trio levels show little change of expression between patients who survived and patients who died from breast cancer. Vav1expression was highest in patients who remained disease free while TIAM-1 expression was much lower in patients who remained disease free compared with those who died from breast cancer.