Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 1 Clinical features of the 44 reported cases of uterine PEComa***

From: Uterine PEComa: appraisal of a controversial and increasingly reported mesenchymal neoplasm

REFERENCE Year Age (yrs) TSC Location Management Outcome
Hornick & Fletcher (39) 2008 34 NS Corpus NS NERM at 33 months
Armah & Parwani (40) 2008 59 No Corpus Hysterectomy/BSO performed 7-years previously for presumed leiomyosarcoma; Renal and pulmonary metastases at current presentation; all resected NERM at 15 months
Liang et al (41) 2008 59 Yes Corpus Hysterectomy/BSO/Pelvic and paraaortic Lymphadenenctomy, omentectomy, appendectomy, peritoneal biopsies; hormonal therapy Extension into cervix at presentation; NERM at 10 months
Gan et al (20) 2007 40 NS Corpus Hysterectomy NERM at 16 months
   33 NS Corpus Hysterectomy NERM at 32 months
   44 NS Corpus Hysterectomy NERM at 52 months
Rammeh Rommani et al (21) 2006 35 No Corpus Excision NERM at 4 months
Azad et al (22) 2006 25 No Cervix Radical hysterectomy, Lymphadenectomy Unavailable or Recent
Folpe et al (13) 2005 59 No Corpus Adjuvant Chemotherapy Liver and Lung metastases at 30 months. Alive with metastases 30 months
   56 No Corpus Adjuvant Chemotherapy and radiotherapy Lung and bone metastases at 11 months; Alive with metastases 11 months
   36 No Corpus Hysterectomy, adjuvant chemotherapy Lung metastases at 12 months, liver metastases 36 months; Death at 39 months
   42 No Corpus No additional surgery or adjuvant therapy NERM at 11 months
   28 No Cervix Hysterectomy and Lymphadenectomy NERM at 36 months
   48 No Cervix Adjuvant Radiotherapy NERM at 21 months
Jeon et al (23) 2005 9 No Corpus Neoadjuvant chemotherapy, Hysterectomy with Lymphadenectomy, Adjuvant Chemotherapy/Radiotherapy Lymph node metastases at presentation, NERM at 18 months
Bernado Vega et al (27) 2005 34 No Corpus Hysterectomy/BSO Unavailable or Recent
Bosincu et al (24) 2005 59 No Corpus Hysterectomy/BSO, omentectomy, abdominal exploration Pelvic recurrence at 6 months; Death at 12 months
   48 No Corpus GnRH analogues, then Hysterectomy NERM at 36 months
Fukunaga (25) 2005 40 No Corpus Hysterectomy/BSO, omentectomy, Adjuvant chemotherapy and radiation. Ovarian and Omental metastases at presentation, Death at 16 months
   30 No Corpus Hysterectomy NERM at 36 months
   36 No Corpus Hysterectomy NERM at 6 months
Fukunaga (25,26) 2004 32 No Corpus Excision NERM at 12 months
Gao et al (28) 2004 60 No Corpus Hysterectomy/BSO, staging Unavailable or Recent
Darai et al (29) 2004 18 No Corpus Excision Pelvic recurrence and lymph node metastases, 6 months, NERM subsequent 24 months
Fadare et al (5) 2004 41 Yes Cervix Hysterectomy/BSO NERM at 35 months
Dimmler et al (32) 2003 61 NS Corpus Hysterectomy Lung metastases at 84 months
Greene et al (30) 2003 79 NS Corpus Hysterectomy/BSO Pelvic and abdominal recurrence at 24 months; Death at 24+ months
Park et al (31) 2003 32 No Corpus Hysterectomy/RSO Right broad ligament/mesovarian extension at presentation; NERM at 18 months
Vang & Kempson (33) 2002 40 No Corpus Excision Unavailable or Recent
   54 No Corpus Hysterectomy/BSO Unavailable or Recent
   56 No Corpus Hysterectomy/BSO Unavailable or Recent
   75 No Corpus Hysterectomy/BSO, Adjuvant Radiotherapy NERM at 31.2 months
   47 No Corpus Hysterectomy/BSO NERM at 1.5 months
   49 Yes Corpus Hysterectomy/BSO NERM at 54 months
   55 No Corpus Hysterectomy/BSO NERM at 2 months
   58 No Corpus Hysterectomy/BSO Unavailable or Recent
Bonnetti et al (34) 2001 19 No Corpus Hysterectomy/BSO/pelvic and inguinal lymphadenectomy, Adjuvant chemotherapy and radiotherapy Metastases to pelvic/inguinal nodes and vaginal extension at presentation. Local recurrence, bone and lung metastases 18 months; no further follow-up
   41 Yes Corpus Hysterectomy/BSO Ovarian metastases at presentation, NERM at 6 months
Michal & Zamecnik* (35) 2000 58 No Corpus Hysterectomy NERM at 48 months
   48 No Corpus Hysterectomy NERM at 48 months
   46 No Corpus Hysterectomy NERM at 12 months
   46 No Corpus Hysterectomy NERM at 12 months
Ruco et al** (38) 1998 56 No Corpus NS Ovary and ileum metastases at presentation
Pea et al (19) 1996 57 No Corpus NS NERM at 24 months
  1. TSC tuberous sclerosis complex; BSO bilateral salpingo-oophorectomy; NERM no evidence of tumor recurrence or metastases. *these authors [35] published a subsequent opinion in which they indicated that their cases are better designated epithelioid smooth muscle neoplasia [36].
  2. **Presumes the same case is being described in references 37 and 38. ***Includes cases published in the English literature before 01/31/08 only, and excludes the case reported in reference 53 due to lack of data.