Table 3 A comparison of the clinicopathologic features of uterine PEComas and uterine epithelioid smooth muscle tumors.
From: Uterine PEComa: appraisal of a controversial and increasingly reported mesenchymal neoplasm
Feature | PEComa | Epithelioid smooth muscle tumors | References |
|---|---|---|---|
Average patient age | 45 years | 48 years | 54,â—™ |
Epithelioid cells | + | + | 8,54,55 |
Spindle cells | + | + | 8,54,55 |
Multinucleated giant cells | + | + | 5,8,13,41,55 |
Stromal Hyalinization | + | + | 8,19,25,33,35, 39,41,54,55 |
Network of capillaries | + | - | 8,13,54,55 |
Clear cells | Usual | Occasional | 8,10–15, 54,55,58,66 |
Eosinophilic cells | Usual | Usual | |
Immunopositivity for at least one melanocytic marker | 100% | Up to 56% | 8,10–15,64 |
Desmin immunopositivity | 49% | 50% | 8,76 |
Smooth muscle actin immunopositivity | 73% | Up to 100% | 8,58,66 |
Proportion of reported cases associated with TSC | 9.1% | No published data | â—™ |