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Table 3 A comparison of the clinicopathologic features of uterine PEComas and uterine epithelioid smooth muscle tumors.

From: Uterine PEComa: appraisal of a controversial and increasingly reported mesenchymal neoplasm

Feature PEComa Epithelioid smooth muscle tumors References
Average patient age 45 years 48 years 54,
Epithelioid cells + + 8,54,55
Spindle cells + + 8,54,55
Multinucleated giant cells + + 5,8,13,41,55
Stromal Hyalinization + + 8,19,25,33,35, 39,41,54,55
Network of capillaries + - 8,13,54,55
Clear cells Usual Occasional 8,10–15, 54,55,58,66
Eosinophilic cells Usual Usual  
Immunopositivity for at least one melanocytic marker 100% Up to 56% 8,10–15,64
Desmin immunopositivity 49% 50% 8,76
Smooth muscle actin immunopositivity 73% Up to 100% 8,58,66
Proportion of reported cases associated with TSC 9.1% No published data
  1. see text; TSC tuberous sclerosis complex