Figure 3

Invasive apocrine carcinoma with desmoplastic stroma (H&E, ×100). (A1), Estrogen receptor shows strong positivity (approximately %80 of the tumor cells) (A2), Progesteron receptor reveals the same features with ER (A3), Cytoplasm expression of HER2/neu, no membranous stainning (A4), Diffuse stainning for gross cystic disease fluid protein (GCDFP15) (A5), Invasive ductal component of the invasive mucinous carcinoma at the perifery of the tumor (H & E, ×40) (B1), H & E sections (×100) (B2), Approximately the whole of the tumor cells shows estrogen receptor positivity (B3), The same stainning features for progesteron (B4), There is no HER2/neu expression, whereas positive control reveals membranous staining (left corner) (B5), Tumor cells arranged in morula-like clusters, reffered to as an ''exfoliative appearance'' (H & E, ×100) (C1), There is no estrogen receptor positivity, whereas positive control reveals staining (left corner) (C2), Approximately 50% of the tumor cells show progesteron receptor positivity (moderate staining) (C3), There is no HER2/neu expression, whereas positive control reveals membranous staining (left corner) (C4), There is stainning for EMA (epithelial membran antigen) at the perifery (C5).