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  1. Content type: Research

    Oesophageal cancer is a major clinical problem with a generally poor prognosis. As a result there has been interest in combining surgery with neoadjuvant chemotherapy to try and improve outcomes, although the ...

    Authors: Brian P Halliday, Richard JE Skipworth, Lucy Wall, Hamish A Phillips, Graeme W Couper, Andrew C de Beaux and Simon Paterson-Brown

    Citation: International Seminars in Surgical Oncology 2007 4:24

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  2. Content type: Review

    although preoperative RT (Radiation Therapy) is becoming the preferred approach for combined treatment of locally advanced rectal adenocarcinoma, no regimen can be now considered as a standard. Since the toxic...

    Authors: Roberto Biffi, Hugo Marsiglia, Barbara Jereczek Fossa, Maria Cristina Leonardi, Domenico Cante, Roberta Lazzari, Antonio Chiappa, Sabine Cenciarelli, Bruno Andreoni, Maria Giulia Zampino and Roberto Orecchia

    Citation: International Seminars in Surgical Oncology 2007 4:23

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  3. Content type: Case report

    Idiopathic granulomatous mastitis is an uncommon, benign entity with a diagnosis of exclusion. The typical clinical presentation of idiopathic granulomatous mastitis often mimics infection or malignancy. As a ...

    Authors: Richard Tuli, Brian J O'Hara, Janet Hines and Anne L Rosenberg

    Citation: International Seminars in Surgical Oncology 2007 4:21

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  4. Content type: Case report

    appendiceal tumours are rare, they may be encountered unexpectedly in any acute or elective abdominal operation, many of these tumours are not appreciated intraoperatively and are diagnosed only during formal ...

    Authors: Moayad M Aljarabah, Neil R Borley and James MD Wheeler

    Citation: International Seminars in Surgical Oncology 2007 4:20

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  5. Content type: Case report

    Idiopathic segmental infarction of the greater omentum (ISIGO) is an uncommon cause of acute abdomen in children and adults and its etiology is rather vague and speculative. The clinical presentation is usuall...

    Authors: Michael Safioleas, Michael Stamatakos, Konstantinos Giaslakiotis, Anastasios Smirnis and Panagiotis Safioleas

    Citation: International Seminars in Surgical Oncology 2007 4:19

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  6. Content type: Research

    The objective of this study was to evaluate serum IGF-I levels in postmenopausal women with breast cancer treated primarily with raloxifene.

    Authors: Benedito B da Silva, Daniel S Moita, Cleicilene G Pires, Edílson C Sousa-Junior, Alesse R dos Santos and Pedro V Lopes-Costa

    Citation: International Seminars in Surgical Oncology 2007 4:18

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  7. Content type: Research

    Accurate determination of the extrahepatic extent and intrahepatic distribution of disease is very important in patients with primary and metastatic liver disease for deciding whether a patient receives potent...

    Authors: Russ A Kuker, Geraldine Mesoloras and Seza A Gulec

    Citation: International Seminars in Surgical Oncology 2007 4:17

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  8. Content type: Commentary

    There are several very obvious and simple solutions for eliminating the "Pitfalls" and for minimizing the risk of occurrence of any perioperative complications associated with placement of chronic indwelling c...

    Authors: Stephen P Povoski

    Citation: International Seminars in Surgical Oncology 2007 4:16

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  9. Content type: Case report

    Medullary thyroid carcinomas (MTC) constitute about 5 to 7 % of thyroid neoplasms. They originate from parafollicular C-cells which can secrete adrenocorticotropic hormone (ACTH) and/or corticotropin-releasing...

    Authors: Michael Sand, Samuel Uecker, Falk G Bechara, Marcos Gelos, Daniel Sand, Till H Wiese and Benno Mann

    Citation: International Seminars in Surgical Oncology 2007 4:15

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  10. Content type: Case report

    Pagets disease of the nipple presents as an eczematous lesion, occurs in 1 – 4% of all female breast carcinoma cases and is invariably associated with underlying malignancy either overt or occult. The majority...

    Authors: Ashok Subramanian, Hilary Birch, Rita McAvinchey and Adam Stacey-Clear

    Citation: International Seminars in Surgical Oncology 2007 4:12

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  11. Content type: Case report

    Sarcomas form a heterogenous group of relatively uncommon malignant tumours which are derived from connective tissue components. In total they comprise approximately 1% of all new cancers diagnosed per year in...

    Authors: Ashok Subramanian, Hilary Birch and Adam Stacey-Clear

    Citation: International Seminars in Surgical Oncology 2007 4:11

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  12. Content type: Case report

    The best possible treatment of metastatic high grade large duodenal GIST is controversial. Surgery (with or without segmental organ resection) remains the principal treatment for primary and recurrent GIST. Ho...

    Authors: Kamran Mohiuddin, Saira Nizami, Asma Munir, Breda Memon and Muhammed A Memon

    Citation: International Seminars in Surgical Oncology 2007 4:9

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  13. Content type: Review

    Venous gangrene (VG) is defined as a clinical triad of skin necrosis and discolouration, documented evidence of venous thromboembolism (VTE) and presence of palpable or doppler- identifiable arterial pulsation...

    Authors: Khalid A Osman, Mohamed H Ahmed, Samir A Abdulla, Tim E Bucknall and Colin A Rogers

    Citation: International Seminars in Surgical Oncology 2007 4:7

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  14. Content type: Case report

    Primary squamous cell carcinoma of the thyroid is an extremely rare neoplasm, with less than 50 cases reported in the world literature. The prognosis is poor with a median survival of less than six months. The...

    Authors: Chintamani, Pranjal Kulshreshtha, Jaiprakash Singh, Nidhi Sugandhi, Anju Bansal, Dinesh Bhatnagar and Sunita Saxena

    Citation: International Seminars in Surgical Oncology 2007 4:8

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  15. Content type: Research

    Angiopoietins (Ang) have been shown to regulate the process of vasculature and angiogenesis in tumour. Different angiopoietins have different roles during the angiogenic process. The current study sought to ex...

    Authors: Khaled A Rmali, Gareth Watkins, Antonio Douglas-Jones, Robert E Mansel and Wen G Jiang

    Citation: International Seminars in Surgical Oncology 2007 4:6

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  16. Content type: Research

    The DNA mismatch repair (MMR) pathway is an important post-replicative repair process. It is involved in the maintenance of genomic stability and MMR genes have therefore been named the proofreaders of replicatin...

    Authors: Chintamani, Binita P Jha, Vimal Bhandari, Anju Bansal, Sunita Saxena and Dinesh Bhatnagar

    Citation: International Seminars in Surgical Oncology 2007 4:5

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  17. Content type: Research

    Precise knowledge of axillary lymph node status is essential in the treatment of operable carcinoma of the breast. For many years, axillary nodal clearance (ANC) has been an integral part of the conventional m...

    Authors: Lucy Mansfield, Isi Sosa, Roberta Dionello, Ash Subramanian, Haresh Devalia and Kefah Mokbel

    Citation: International Seminars in Surgical Oncology 2007 4:4

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  18. Content type: Case report

    The histogenesis of the hepatic sarcoma and its association with hamartoma is not well understood. We hereby present a Chinese patient with hepatic angiosarcoma arising from an adult mesenchymal hamartoma of l...

    Authors: Qiang Li, Jian Wang, Yan Sun, Yunlong Cui and Xishan Hao

    Citation: International Seminars in Surgical Oncology 2007 4:3

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  19. Content type: Case report

    A 78-year-old woman was diagnosed with a proximal gastric adenocarcinoma and underwent an elective D2 total gastrectomy with splenectomy. Subsequent histopathology revealed the presence of another tumour at th...

    Authors: Iraklis E Katsoulis, Manuela Bossi, Paul I Richman and Jeremy I Livingstone

    Citation: International Seminars in Surgical Oncology 2007 4:2

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  20. Content type: Review

    We report our results of a selective approach to primary direct appositional vaginal repair versus transverse rectus abdominis flap repair (TRAM) in patients with extensive rectal/anal cancer or in cases with ...

    Authors: Andrew P Zbar, Radhakanth K Shenoy and Antonio Chiappa

    Citation: International Seminars in Surgical Oncology 2007 4:1

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  21. Content type: Case report

    The concept of the sentinel node describes a primary or sentinel lymph node (SLN), which exists and through which tumour cells from a primary tumour in a particular location must first travel to spread to a pa...

    Authors: Lucy Mansfield, Haresh Devalia, Nadeem Rehman and Kefah Mokbel

    Citation: International Seminars in Surgical Oncology 2006 3:39

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  22. Content type: Research

    Osteosarcoma is the most common primary malignant bone tumour in children and young adults. Despite advances in the diagnosis and management of osteosarcoma, there have been few recent studies describing the e...

    Authors: Judith Zhi-Yie Tan, Stephen M Schlicht, Gerard J Powell, David Thomas, John L Slavin, Peter J Smith and Peter FM Choong

    Citation: International Seminars in Surgical Oncology 2006 3:38

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  23. Content type: Review

    There is some evidence that breast cancer surgery during the luteal phase in pre-menopausal women is associated with a better clinical outcome, however the evidence for this is still equivocal.

    Authors: Anushka Chaudhry, Michael L Puntis, Panos Gikas and Kefah Mokbel

    Citation: International Seminars in Surgical Oncology 2006 3:37

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  24. Content type: Review

    Accurate staging of rectal cancer is essential for selecting patients who can undergo sphincter-preserving surgery. It may also identify patients who could benefit from neoadjuvant therapy. Clinical staging is...

    Authors: Ali A Siddiqui, Yomi Fayiga and Sergio Huerta

    Citation: International Seminars in Surgical Oncology 2006 3:36

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  25. Content type: Commentary

    Despite the lack of randomised controlled trials and paucity of the published data, the current evidence suggests that the post-mastectomy radiation therapy (PMRT) does not represent a contraindication to skin...

    Authors: Ramia Mokbel and Kefah Mokbel

    Citation: International Seminars in Surgical Oncology 2006 3:35

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  26. Content type: Review

    To highlight the salient features of metastatic malignancies involving the penis, with special reference to the primary tumour sites, metastatic mechanisms, clinical features, differential diagnosis, treatment...

    Authors: Jacob Cherian, Sreekumar Rajan, Ali Thwaini, Yaser Elmasry, Tariq Shah and Rajiv Puri

    Citation: International Seminars in Surgical Oncology 2006 3:33

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  27. Content type: Case report

    A 58 year old lady presented with a right breast cancer and a prior history of malignant melanoma excised from the right chest wall eight years previously. An abnormal axillary lymph node resected contained fe...

    Authors: Kirstin A Carswell, Kasim A Behranwala, Ashutosh Nerurkar A and Gerald PH Gui

    Citation: International Seminars in Surgical Oncology 2006 3:32

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  28. Content type: Editorial

    There is overwhelming evidence that optimal adjuvant endocrine therapy for hormone sensitive breast cancer in postmenopausal women should include a third generation aromatase inhibitor (AI). On current evidenc...

    Authors: Ramia Mokbel, Isabella Karat and Kefah Mokbel

    Citation: International Seminars in Surgical Oncology 2006 3:31

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  29. Content type: Review

    Aim of the present study was to investigate the feasibility and long-term results of focused radioguided parathyroidectomy using a "low" 37 MBq (1 mCi) 99mTc-sestamibi dose protocol compared to conventional "high...

    Authors: Domenico Rubello, Adil Al-Nahhas, Giuliano Mariani, Milton D Gross, Lucia Rampin and Maria Rosa Pelizzo

    Citation: International Seminars in Surgical Oncology 2006 3:30

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  30. Content type: Research

    Breast carcinoma is the most common malignancy among women and it has a major impact on mortality. Studies of primary chemoprevention with tamoxifen have generated high expectations and considerable success ra...

    Authors: Juarez Antônio de Sousa, Gil Facina, Benedito Borges da Silva and Luiz Henrique Gebrim

    Citation: International Seminars in Surgical Oncology 2006 3:29

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  31. Content type: Research

    The purpose of the study was to determine the outcome of all patients with endometrial adenocarcinoma cancer treated by laparoscopic hysterectomy at our institution, many of whom were high-risk for surgery.

    Authors: Susan F Willis, Desmond Barton and Thomas EJ Ind

    Citation: International Seminars in Surgical Oncology 2006 3:28

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  32. Content type: Case report

    Renal cell carcinoma is well known for its frequency to metastasise, particularly to lungs, liver, bones and brain. Metastasis to the skin is much less common. Presentation as a result of the skin lesion is ev...

    Authors: Neil A Porter, Helen L Anderson and Saad Al-Dujaily

    Citation: International Seminars in Surgical Oncology 2006 3:27

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  33. Content type: Case report

    Radiation induced angiosarcomas (RIA) can affect breast cancer patients who had radiotherapy following conservative breast surgery. They are very rare tumors and often their diagnosis is delayed due to their b...

    Authors: M Tahir, P Hendry, L Baird, NA Qureshi, D Ritchie and P Whitford

    Citation: International Seminars in Surgical Oncology 2006 3:26

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  34. Content type: Case report

    Carcinoma within a long-standing fistula-in-ano is rare and may be defined by specific neoplastic involvement of the fistulous track in the absence of rectal mucosal carcinoma. The presence of a carcinoma of m...

    Authors: Nemandra Sandiford, Patsy R Prussia, Antonio Chiappa and Andrew P Zbar

    Citation: International Seminars in Surgical Oncology 2006 3:25

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  35. Content type: Case report

    Metaplastic breast carcinoma (MBC) is a rare neoplasm containing a mixture of epithelial and mesenchymal elements. The epithelial component is usually ductal carcinoma but may include other variants of breast ...

    Authors: Corrine Wong, Chris Wright, Angela Colclough and Simon Marsh

    Citation: International Seminars in Surgical Oncology 2006 3:23

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  36. Content type: Case report

    Tumor spread beyond the peritoneal cavity in cases of papillary serous adenocarcinoma of the unknown primary (CUP) is a rare late event and carries a poor prognosis.

    Authors: Takeshi Todoroki, Souichiro Murata, Yuji Nakagawa, Nobuhiro Ohkohchi and Yukio Morishita

    Citation: International Seminars in Surgical Oncology 2006 3:22

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  37. Content type: Research

    Telomerase is a ribonucleoprotein enzyme that synthesises telomeres after cell division and maintains chromosomal stability leading to cellular immortalization. Telomerase has been associated with negative pro...

    Authors: Saied Hosseini-Asl, Morteza Atri, Mohammad H Modarressi, Mohamed Salhab, Kefah Mokbel and Parvin Mehdipour

    Citation: International Seminars in Surgical Oncology 2006 3:20

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  38. Content type: Research

    Resection and replacement of the inferior vena cava to remove malignant disease is a formidable procedure. The purpose of this review is to describe our experience with regard to patient selection, operative t...

    Authors: Patrizio Castelli, Roberto Caronno, Gabriele Piffaretti, Matteo Tozzi, Chiara Lomazzi, Gianlorenzo Dionigi, Luigi Boni and Renzo Dionigi

    Citation: International Seminars in Surgical Oncology 2006 3:19

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  39. Content type: Case report

    This article is a case report of a high grade, radio-induced, breast malignant fibrous histiocytoma (undifferentiated high grade pleomorphic sarcoma), which developed in a 44-year old female, seven years after...

    Authors: Claudio Almeida Quadros, Alessandro Vasconcelos, Roque Andrade, Rogério Santos Ramos, Eduardo Studart, Geraldo Nascimento and André Trajano

    Citation: International Seminars in Surgical Oncology 2006 3:18

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  40. Content type: Research

    Mammary ductoscopy (MD) is a newly developed endoscopic technique that allows direct visualisation of the mammary ductal epithelium using sub-millimetre fiberoptic microendoscopes inserted through the ductal o...

    Authors: W Al Sarakbi, M Salhab and K Mokbel

    Citation: International Seminars in Surgical Oncology 2006 3:16

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  41. Content type: Review

    Adenoid cystic carcinoma (ACC) of the breast is a rare neoplasm accounting for 0.1% of all breast carcinomas, and presenting most commonly as a painful breast mass. In contrast to the aggressive nature of ACC ...

    Authors: Alaa A Muslimani, Manmeet S Ahluwalia, Christopher T Clark and Hamed A Daw

    Citation: International Seminars in Surgical Oncology 2006 3:17

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  42. Content type: Case report

    Primary intra-abdominal malignant mesenchymal tumours are very rare and there are not many cases of visceral malignant fibrous histiocytoma in the English literature. We report a new case of abdominal malignan...

    Authors: NA Qureshi, MT Hallissey, JW Fielding and D Gourevitch

    Citation: International Seminars in Surgical Oncology 2006 3:15

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  43. Content type: Review

    To review evidence concerning the oncological safety of performing skin-sparing mastectomy (SSM) for invasive breast cancer and ductal carcinoma in situ (DCIS). Furthermore, the evidence concerning RT in relat...

    Authors: GH Cunnick and K Mokbel

    Citation: International Seminars in Surgical Oncology 2006 3:14

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